Post by cddexter on Aug 14, 2013 13:36:46 GMT -5
One the bits I'll be tossing (ref thread on cleaning out files under General): This is from a company called Genetic Visions, based in WI (at the time the only lab doing E+ testing in North America). Sixteen years ago I used to deal with Mike Cowan, not sure he's still there. I used GV for the DNA testing that proved E+ existed and was red in Dexters, and proved that dun was NOT a standard dilute, nor E+ (as it is in Jerseys and Brown Swiss). In those days, tests were $60 each.
The original blurb was on the old heat sensitive fax paper and has almost faded away. They were a great company to deal with, and John Potter, on my recommendation, used them for the DNA work he did on the TYRP1 (brown/dun) study. He found them very helpful,. too. Since there is a rise in interest in Dexters for milk, and cheese has become of interest, thought this info might be useful.
From Genetic Visions:
Genes affecting milk yield and composition can have different forms. For example, the milk protein gene kappa-casein has two forms. One variant is commonly referred to as the A allele, whereas, the other form is denoted as the B allele. If the variants of a gene are associated with important traits, these 'genetic markers' can be used to indicate which animals are likely to have enhanced genetic value and which ones do not. This information can then be used to supplement pedigree information and may make your selection decision easier.
Kappa-casein variants of milk have been associated with differences in manufacturing characteristics. Milk from cows with kappa-casein genotype BB has been reported to yield more cheese and to have better cheese manufacturing characteristics than milk from cows kappa-casein genotype AA.
Our work at Genetic Visions, Inc. has shown that the effects of kappa-casein may differ by sire family. We compared PTAs for yield traits with kappa-casein genotype among sons of one elite Holstein sire. Within this sire family, sons with kappa-casein genotype BB had increased transmitting abilities for milk yield of 410 lbs. and there was a relative exchange fat for protein (8.15 lbs. more protein than fat).
All cattle will have one of the three kappa-casein genotypes: AA, AB or BB. The table (to the left) shows the approxi8mate distribution of genotype by dairy breed. The numbers may vary from herd to herd depending upon the sire used.
Market assisted selection can be applied to all animals regardless of age, sex or breed. However, the greatest application of genetic markers is when selecting among animals with similar or identical pedigrees or when lactation or performance information is lacking.
Breed AA AB BB
Holstein 67% 30% 3%
Guernsey 53% 40% 7%
Jersey 2% 25% 74%
Brown Swiss 11% 44% 45%
Genetic Visions, Inc., 200 S. Fish Hatchery Rd., Madison, WI 53711 ph (608) 274-5340
Carol back again: I think it would prove very interesting to determine which sires carried which alleles. With all the money it's amassing, I wonder if the assn. would be interested in paying for the tests for AI bulls (at least) in the interests of a service to its members. (and let's not get bogged down in petty fights about how one breeder might benefit to the detriment of another. This isn't about personalities, it's about what matters within the breed!). The assn. didn't cough up a dime for testing for pha, that cost fell on a few dedicated breeders who've never had recognition for their service. This would be a good time and place for the BoD to take responsibility for breed management....imo. Cheers, c.
The original blurb was on the old heat sensitive fax paper and has almost faded away. They were a great company to deal with, and John Potter, on my recommendation, used them for the DNA work he did on the TYRP1 (brown/dun) study. He found them very helpful,. too. Since there is a rise in interest in Dexters for milk, and cheese has become of interest, thought this info might be useful.
From Genetic Visions:
Genes affecting milk yield and composition can have different forms. For example, the milk protein gene kappa-casein has two forms. One variant is commonly referred to as the A allele, whereas, the other form is denoted as the B allele. If the variants of a gene are associated with important traits, these 'genetic markers' can be used to indicate which animals are likely to have enhanced genetic value and which ones do not. This information can then be used to supplement pedigree information and may make your selection decision easier.
Kappa-casein variants of milk have been associated with differences in manufacturing characteristics. Milk from cows with kappa-casein genotype BB has been reported to yield more cheese and to have better cheese manufacturing characteristics than milk from cows kappa-casein genotype AA.
Our work at Genetic Visions, Inc. has shown that the effects of kappa-casein may differ by sire family. We compared PTAs for yield traits with kappa-casein genotype among sons of one elite Holstein sire. Within this sire family, sons with kappa-casein genotype BB had increased transmitting abilities for milk yield of 410 lbs. and there was a relative exchange fat for protein (8.15 lbs. more protein than fat).
All cattle will have one of the three kappa-casein genotypes: AA, AB or BB. The table (to the left) shows the approxi8mate distribution of genotype by dairy breed. The numbers may vary from herd to herd depending upon the sire used.
Market assisted selection can be applied to all animals regardless of age, sex or breed. However, the greatest application of genetic markers is when selecting among animals with similar or identical pedigrees or when lactation or performance information is lacking.
Breed AA AB BB
Holstein 67% 30% 3%
Guernsey 53% 40% 7%
Jersey 2% 25% 74%
Brown Swiss 11% 44% 45%
Genetic Visions, Inc., 200 S. Fish Hatchery Rd., Madison, WI 53711 ph (608) 274-5340
Carol back again: I think it would prove very interesting to determine which sires carried which alleles. With all the money it's amassing, I wonder if the assn. would be interested in paying for the tests for AI bulls (at least) in the interests of a service to its members. (and let's not get bogged down in petty fights about how one breeder might benefit to the detriment of another. This isn't about personalities, it's about what matters within the breed!). The assn. didn't cough up a dime for testing for pha, that cost fell on a few dedicated breeders who've never had recognition for their service. This would be a good time and place for the BoD to take responsibility for breed management....imo. Cheers, c.